What it does: L-Citrulline supports the conversion of ammonia into urea for elimination and helps increase nitric oxide levels, which relaxes blood vessels and enhances blood flow throughout the body.
How it is used: This amino acid is commonly used in sports nutrition and pre-workout supplements to support exercise endurance, reduce muscle fatigue, and aid post-exercise recovery.
Natural sources and supplement forms: Watermelon is the richest natural source of L-citrulline, with lower amounts present in other melons and certain vegetables. Supplement forms include pure L-citrulline powder, capsules, and L-citrulline malate (combined with malic acid).
Why it appears in supplement formulas: L-Citrulline is valued for its ability to help promote circulation, support stamina, and improve athletic performance by encouraging natural nitric oxide production.
What to know before use: L-Citrulline is generally well tolerated, but people on blood pressure or cardiovascular medications should consult a healthcare provider before starting supplementation.
L-Citrulline: Watermelon’s Secret Amino Acid
L-Citrulline gets its name from Citrullus, the Latin word for watermelon, because it was first discovered in watermelon pulp over a century ago. This non-essential amino acid is a key player in the body’s urea cycle, helping convert ammonia to urea for excretion. Naturally present in watermelon, L-citrulline is often used in supplements to support natural metabolic pathways.
